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Urine Specimen Drug Abuse Test Kit , 12 Panel Drug Test Cup 4mm Strip Gold Colloidal

Categories Drug Abuse Test Kit
Brand Name: New Life
Model Number: Dipcard/cassette/strip
Certification: ISO13485, CE
Place of Origin: China
MOQ: 5000pcs
Price: USD0.5-USD5
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 2000000pcs/month
Delivery Time: 20-30days
Packaging Details: 1pc/pouch, 25pcs/box
Method: Gold Colloidal
Format: drug cup
Specimen: Urine
Testing time: 5-15 minutes
Shelf Life: 24 Months
Application: all kinds of drug
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    Urine Specimen Drug Abuse Test Kit , 12 Panel Drug Test Cup 4mm Strip Gold Colloidal

    Multiple drug test cup with all kinds of drug abuse test,4mm strip Gold colloidal method,medical


    Intended of Use


    The One Step Multi-Drug Screen Test cup is a lateral flow chromatographic immunoassay for the qualitative detection of multiple drugs and drug metabolites in urine at the following cut-off concentrations:


    TestCalibratorCut-off (ng/mL)
    Amphetamine (AMP 1000)d-Amphetamine1,000
    Amphetamine (AMP 500)d-Amphetamine500
    Amphetamine (AMP 300)d-Amphetamine300
    Barbiturates (BAR 300)Secobarbital300
    Barbiturates (BAR 200)Secobarbital200
    Benzodiazepines (BZO 500)Oxazepam500
    Benzodiazepines (BZO 300)Oxazepam300
    Benzodiazepines (BZO 200)Oxazepam200
    Benzodiazepines (BZO 100)Oxazepam100
    Buprenorphine (BUP 10)Buprenorphine10
    Buprenorphine (BUP 5)Buprenorphine5
    Cocaine (COC 300)Benzoylecgonine300
    Cocaine (COC200)Benzoylecgonine200
    Cocaine (COC 100)Benzoylecgonine100
    Cocaine (COC 150)Benzoylecgonine150
    Marijuana (THC150)11-nor-Δ9pHC-9 COOH150
    Marijuana (THC 50)11-nor-Δ9pHC-9 COOH50
    Marijuana (THC 25)11-nor-Δ9pHC-9 COOH25
    Methadone (MTD 300)Methadone300
    Methadone (MTD 200)Methadone200
    Methamphetamine (MET 1,000)d-Methamphetamine1,000
    Methamphetamine (MET 500)d-Methamphetamine500
    Methamphetamine (MET 300)d-Methamphetamine300
    Methylenedioxymethamphetamine (MDMA 500)d,l-Methylenedioxymethamphetamine500
    Methylenedioxymethamphetamine (MDMA 1,000)d,l-Methylenedioxymethamphetamine1,000
    Morphine (MOP 300)Morphine300
    Morphine (MOP 100)Morphine100
    Opiate (MOP 2000)Morphine2,000
    Methaqualone(MQL)Methaqualone300
    Phencyclidine (PCP)Phencyclidine25
    Propoxyphene (PPX)Propoxyphene300
    Tricyclic Antidepressants (TCA)Nortriptyline1,000
    Tramadol (TML 100)Tramadol100
    Tramadol (TML 200)Tramadol200
    Tramadol (TML300)Tramadol300
    Ketamine (KET 1,000)Ketamine1,000
    Ketamine (KET 500)Ketamine500
    Ketamine (KET 300)Ketamine300
    Ketamine (KET 300)Ketamine100
    Oxycodone (OXY)Oxycodone100
    Cotinine(COT 200)Cotinine200
    Cotinine(COT 100)Cotinine100
    2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP 300)2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine300
    2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP 100)2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine100
    Fentanyl(FYL20)Norfentanyl20
    Fentanyl(FYL10)Norfentanyl10
    Synthetic Marijuana(K2 50)JWH -018, JWH- 07350
    Synthetic Marijuana(K2 30 )JWH -018, JWH- 07330
    6-mono-aceto-morphine (6-MAM)6-mono-aceto-morphine10
    Clonazepam (CLO400)Clonazepam400
    Clonazepam (CLO150)Clonazepam150
    Benzodiazepines (DIA)Benzodiazepines300
    Ethyl Glucuronide(ETG500)Ethyl Glucuronide500
    Ethyl Glucuronide(ETG1000)Ethyl Glucuronide1000
    ACE (Acetaminophen)Acetaminophen5000
    CAT (Cathinone)Cathinone150
    LSD 20 (Lysergic Acid Diethylamide)Lysergic Acid Diethylamide20
    LSD 50 (Lysergic Acid Diethylamide)Lysergic Acid Diethylamide50
    MDA(3,4-Methylenedioxyamphetamine)3,4-Methylenedioxyamphetamine500
    MDPV (3, 4-methylenedioxypyrovalerone)3, 4-methylenedioxypyrovalerone1000
    MPD(Methylphenidate)Methylphenidate300
    Zolpidem (ZOL)Zolpidem50
    TestCalibratorCut-off
    Alcohol(ALC)Alcohol0.02%

    Configurations of the One Step Multi-Drug Screen Test cup with the Integrated come with any combination of the above listed drug analytes. This assay provides only a preliminary analytical test result. A more specific alternate chemical method must be used in order to obtain a confirmed analytical result. Gas chromatography/mass spectrometry (GC/MS) is the preferred confirmatory method. Clinical consideration and professional judgment should be applied to any drug of abuse test result, particularly when preliminary positive results are indicate


    Summary


    1.3.1 Amphetamine


    Amphetamine is a Schedule II controlled substance available by prescription (Dexedrine®) and is also available on the illicit market. Amphetamines are a class of potent sympathomimetic agents with therapeutic applications. They are chemically related to the human body’s natural catecholamines: epinephrine and norepinephrine. Acute higher doses lead to enhanced stimulation of the central nervous system (CNS) and induce euphoria, alertness, reduced appetite, and a sense of increased energy and power. Cardiovascular responses to amphetamines include increased blood pressure and cardiac arrhythmias. More acute responses produce anxiety, paranoia, hallucinations, and psychotic behavior. The effects of Amphetamines generally last 2-4 hours following use and the drug has a half-life of 4-24 hours in the body. About 30% of amphetamines are excreted in the urine in unchanged form, with the remainder as hydroxylated and deaminated derivatives.


    1.3.2 Barbiturates


    Barbiturates are CNS depressants. They are used therapeutically as sedatives, hypnotics, and anticonvulsants barbiturates are almost always taken orally as capsules or tablets. The effects resemble those of intoxication with alcohol. Chronic use of barbiturates leads to tolerance and physical dependence.

    Short-acting barbiturates taken at 400 mg/day for 2-3 months can produce a clinically significant degree of physical dependence. Withdrawal symptoms experienced during periods of drug abstinence can be severe enough to cause death.

    Only a small amount (less than 5%) of most barbiturates are excreted unaltered in the urine.

    The approximate detection time limits for barbiturates are:

    Short acting (e.g. Secobarbital)100 mg PO (oral)4.5 days
    Long acting (e.g. Phenobarbital)400 mg PO (oral)7 days

    1.3.3 Benzodiazepines


    Benzodiazepines are medications that are frequently prescribed for the symptomatic treatment of anxiety and sleep disorders. They produce their effects via specific receptors involving a neurochemical called gamma aminobutyric acid (GABA). Because they are safer and more effective, Benzodiazepines have replaced Barbiturates in the treatment of both anxiety and insomnia. Benzodiazepines are also used as sedatives before some surgical and medical procedures, and for the treatment of seizure disorders and alcohol withdrawal.

    Risk of physical dependence increases if Benzodiazepines are taken regularly (e.g., daily) for more than a few months, especially at higher than normal doses. Stopping abruptly can bring on such symptoms as trouble sleeping, gastrointestinal upset, feeling unwell, loss of appetite, sweating, trembling, weakness, anxiety and changes in perception. Only trace amounts (less than 1%) of most Benzodiazepines are excreted unaltered in the urine; most of the concentration in urine is conjugated drug. The detection period for the Benzodiazepines in the urine is 3-7 days.


    1.3.4 Buprenorphine


    Buprenorphine is a potent analgesic often used in the treatment of opioid addiction. The drug is sold under the trade names Subutex™, Buprenex™, Temgesic™ and Suboxone™, which contain Buprenorphine HCl alone or in combination with Naloxone HCl. Therapeutically, Buprenorphine is used as a substitution treatment for opioid addicts. Substitution treatment is a form of medical care offered to opiate addicts (primarily heroin addicts) based on a similar or identical substance to the drug normally used. In substitution therapy, Buprenorphine is as effective as Methadone but demonstrates a lower level of physical dependence. Concentrations of free Buprenorphine and Norbuprenorphine in urine may be less than 1 ng/ml after therapeutic administration, but can range up to 20 ng/ml in abuse situations.10 The plasma half life of Buprenorphine is 2-4 hours.10 While complete elimination of a single dose of the drug can take as long as 6 days, the window of detection for the parent drug in urine is thought to be approximately 3 days.

    Substantial abuse of Buprenorphine has also been reported in many countries where various forms of the drug are available. The drug has been diverted from legitimate channels through theft, doctor shopping, and fraudulent prescriptions, and been abused via intravenous, sublingual, intranasal and inhalation routes.


    1.3.5 Cocaine


    Cocaine is a potent central nervous system stimulant and a local anesthetic. Initially, it brings about extreme energy and restlessness while gradually resulting in tremors, over-sensitivity and spasms. In large amounts, cocaine causes fever, unresponsiveness, difficulty in breathing and unconsciousness.

    Cocaine is often self-administered by nasal inhalation, intravenous injection and free-base smoking. It is excreted in the urine in a short time primarily as benzoylecgonine.3,4 Benzoylecgonine, a major metabolite of cocaine, has a longer biological half-life (5-8 hours) than cocaine (0.5-1.5 hours), and can generally be detected for 24-48 hours after cocaine exposure.4


    1.3.6 Marijuana


    THC (D9petrahydrocannabinol) is the primary active ingredient in cannabis (marijuana). When smoked or orally administered, THC produces euphoric effects. Users have impaired shortperm memory and slowed learning. They may also experience transient episodes of confusion and anxiety. Longperm, relatively heavy use may be associated with behavioral disorders. The peak effect of marijuana administered by smoking occurs in 20-30 minutes and the duration is 90-120 minutes after one cigarette. Elevated levels of urinary metabolites are found within hours of exposure and remain detectable for 3-10 days after smoking. The main metabolite excreted in the urine is 11-nor-D9petrahydrocannabinol-9-carboxylic acid (THC-COOH).


    1.3.7 Methadone


    Methadone is a narcotic analgesic prescribed for the management of moderate to severe pain and for the treatment of opiate dependence (heroin, Vicodin, Percocet, morphine). The pharmacology of oral methadone is very different from IV methadone. Oral methadone is partially stored in the liver for later use. IV methadone acts more like heroin. In most states you must go to a pain clinic or a methadone maintenance clinic to be prescribed methadone.

    Methadone is a long acting pain reliever producing effects that last from twelve to forty-eight hours. Ideally, methadone frees the client from the pressures of obtaining illegal heroin, from the dangers of injection, and from the emotional roller coaster that most opiates produce. Methadone, if taken for long periods and at large doses, can lead to a very long withdrawal period. The withdrawals from methadone are more prolonged and troublesome than those provoked by heroin cessation, yet the substitution and phased removal of methadone is an acceptable method of detoxification for patients and therapists.


    1.3.8 Methamphetamine


    Methamphetamine is an addictive stimulant drug that strongly activates certain systems in the brain. Methamphetamine is closely related chemically to Amphetamine, but the central nervous system effects of Methamphetamine are greater. Methamphetamine is made in illegal laboratories and has a high potential for abuse and dependence. The drug can be taken orally, injected, or inhaled. Acute higher doses lead to enhanced stimulation of the central nervous system and induce euphoria, alertness, reduced appetite, and a sense of increased energy and power. Cardiovascular responses to Methamphetamine include increased blood pressure and cardiac arrhythmias. More acute responses produce anxiety, paranoia, hallucinations, psychotic behavior, and eventually, depression and exhaustion.

    The effects of Methamphetamine generally last 2-4 hours and the drug have a half-life of 9-24 hours in the body. Methamphetamine is excreted in the urine primarily as Amphetamine, and oxidized and deaminated derivatives. However, 10-20% of Methamphetamine is excreted unchanged. Thus, the presence of the parent compound in the urine indicates Methamphetamine use. Methamphetamine is generally detectable in the urine for 3-5 days, depending on urine pH level.


    1.3.9 Methylenedioxymethamphetamine


    Methylenedioxymethamphetamine (ecstasy) is a designer drug first synthesized in 1914 by a German drug company for the treatment of obesity.5 Those who take the drug frequently report adverse effects, such as increased muscle tension and sweating. MDMA is not clearly a stimulant, although it has, in common with amphetamine drugs, a capacity to increase blood pressure and heart rate. MDMA does produce some perceptual changes in the form of increased sensitivity to light, difficulty in focusing, and blurred vision in some users. Its mechanism of action is thought to be via release of the neurotransmitter serotonin. MDMA may also release dopamine, although the general opinion is that this is a secondary effect of the drug (Nichols and Oberlender, 1990). The most pervasive effect of MDMA, occurring in virtually all people who took a reasonable dose of the drug, was to produce a clenching of the jaws.


    1.3.10 Morphine/Opiate


    Morphine/Opiate refers to any drug that is derived from the opium poppy, including the natural products, morphine and codeine, and the semi-synthetic drugs such as heroin. Morphine/Opiate is more general, referring to any drug that acts on the opioid receptor.

    Opioid analgesics comprise a large group of substances which control pain by depressing the CNS. Large doses of morphine can produce higher tolerance levels, physiological dependency in users, and may lead to substance abuse. Morphine is excreted unmetabolized, and is also the major metabolic product of codeine and heroin. Morphine is detectable in the urine for several days after an opiate dose.


    1.3.11 Phencyclidine


    Phencyclidine, also known as PCP or Angel Dust, is a hallucinogen that was first marketed as a surgical anesthetic in the 1950’s. It was removed from the market because patients receiving it became delirious and experienced hallucinations.

    PCP is used in powder, capsule, and tablet form. The powder is either snorted or smoked after mixing it with marijuana or vegetable matter. PCP is most commonly administered by inhalation but can be used intravenously, intra-nasally, and orally. After low doses, the user thinks and acts swiftly and experiences mood swings from euphoria to depression. Self-injurious behavior is one of the devastating effects of PCP.

    PCP can be found in urine within 4 to 6 hours after use and will remain in urine for 7 to 14 days, depending on factors such as metabolic rate, user’s age, weight, activity, and diet.6 PCP is excreted in the urine as an unchanged drug (4% to 19%) and conjugated metabolites (25% to 30%).


    Test Principle


    The One Step Multi-Drug Screen Test cup is an immunoassay based on the principle of competitive binding. Drugs which may be present in the urine specimen compete against their respective drug conjugate for binding sites on their specific antibody. During testing, a urine specimen migrates upward by capillary action. A drug, if present in the urine specimen below its cut-off concentration, will not saturate the binding sites of its specific antibody. The antibody will then react with the drug-protein conjugate and a visible colored line will show up in the test region of the specific drug strip. The presence of drug above the cut-off concentration will saturate all the binding sites of the antibody. Therefore, the colored line will not form in the test region. A drug-positive urine specimen will not generate a colored line in the specific test region of the strip because of drug competition, while a drug-negative urine specimen will generate a line in the test region because of the absence of drug competition. To serve as a procedural control, a colored line will always appear at the control region, indicating that proper volume of specimen has been added and membrane wicking has occurred

    Direction for use


    Allow the test cup, urine specimen, and/or controls to equilibrate to room temperature (15-30°C) prior to testing.


    1. Bring the pouch to room temperature before opening it. Remove the cup from the sealed pouch and use it as soon as possible.
    2. Donor provides specimen.
    3. Technician replaces and secures cap while the cup is on a flat surface.
    4. Donor dates and initials the security seal and attaches the security seal over the cup cap.
    5. Technician peels off label to reveal adulteration strip(s), if applicable.
    6. Technician peels off the label on the multi-drug test card to view results.
    7. The adulteration strip(s), if applicable, should be read between 3-5 minutes. Compare the colors on the adulteration strip to the color chart. If the results indicate adulteration, do not read the drug test results.
    8. If preliminary positive results are observed, please send the cup to the laboratory for confirmation.

    INTERPRETATION OF RESULTS


    NEGATIVE:* Two lines appear. One red line should be in the control region (C), and another apparent red or pink line adjacent should be in the test region (Drug/T). This negative result indicates that the drug concentration is below the detectable level. *NOTE: The shade of red in the test line region (Drug/T) will vary, but it should be considered negative whenever there is even a faint pink line.


    POSITIVE: One red line appears in the control region (C). No line appears in the test region (Drug/T). This positive result indicates that the drug concentration is above the detectable level.


    INVALID: Control line fails to appear. Insufficient sample volume or not conducting the test as instructed are the most likely reasons for control line failure. Review the procedure and repeat the test using a new test device.


    QUALITY CONTROL


    A procedural control is included in the test. A line appearing in the control region

    (C) is considered an internal procedural control. It confirms sufficient specimen volume, adequate membrane wicking and correct procedural technique.

    Control standards are not supplied with this kit. However, it is recommended that positive and negative controls be tested as good laboratory practice to confirm the test procedure and to verify proper test performance.



    ORIENT NEW LIFE MEDICAL CO., LTD.
    Contact:Jerry Meng
    Email:Jerry @ newlifebiotest .com
    Tel.+86 18657312116
    SKYPEenetjerry
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